At Sapio Sciences, we believe that real scientific progress happens when brilliant minds are empowered by the right technology. That belief was affirmed by a recent peer-reviewed study published in Journal of Chromatography A, which showcases groundbreaking advancements in high-throughput sample processing by Janssen Research & Development, a division of Johnson & Johnson. The team here at Sapio is proud to have played an integral role in this scientific achievement.

Breakthroughs in High-Throughput Analytical Science

Janssen’s work focused on the development and implementation of an ultra-high-throughput sample processing system designed to accelerate large-scale bioanalysis. This platform enabled the generation of over 160,000 high-quality chromatographic injections in less than three months—a feat that sets new benchmarks for analytical chemistry, automation, and throughput in pharmaceutical R&D.

More than just speed, Janssen’s platform achieved remarkable data quality and reliability, ensuring consistency across thousands of samples. Their innovation wasn’t just technical—it was strategic, enabling a more agile and scalable approach to preclinical and clinical sample processing.

Sapio LIMS: The Digital Backbone Behind the Science

While the analytical platform itself stole the scientific spotlight, this high-throughput operation could not have been possible without the robust, configurable informatics infrastructure running behind the scenes—powered by the Sapio LIMS.

Janssen utilized Sapio’s flexible LIMS solution to orchestrate every aspect of their ultra-high-throughput LIMS-enabled workflow. From dynamic sample tracking and automated instrument integration to batch management and QC verification, our platform ensured end-to-end traceability, regulatory compliance, and data integrity.

Because Sapio LIMS is built with a no/low-code architecture, the Janssen team was able to rapidly configure workflows without waiting on developer cycles. That agility was critical in adapting to evolving project requirements during the study. Scientists were able to operate within a unified, science-aware environment—visualizing and managing their data in real time, without ever losing context.

From Complexity to Clarity: Unifying the Lab

One of the core challenges in large-scale biopharma research is the fragmentation of data and tools. Janssen overcame this by implementing a cohesive, integrated platform where LIMS, automation systems, and analytical instrumentation worked in lockstep. That ecosystem was made possible through Sapio’s open architecture and extensive integration capabilities.

This isn’t just about scale—it’s about clarity and control. With Sapio, Janssen was able to achieve:

  • Real-time sample tracking and batching
  • Automated QC checks at every stage
  • Built-in scientific tools for method validation and analytics
  • Total regulatory traceability (21 CFR Part 11 compliance)

What This Means for the Future of Biopharma R&D

Janssen’s work demonstrates that the next frontier of drug discovery isn’t just about faster analytics—it’s about building digital infrastructures that adapt and scale with science itself.

As scientific questions grow more complex, the lab needs to respond with systems that unify execution and insight. With our unified informatics platform—integrating LIMS, ELN, and our Scientific Data Cloud, Sapio empowers organizations to collapse silos, accelerate discovery, and amplify impact.

Ready to Modernize Your Lab?

Explore how a flexible LIMS solution like Sapio can help your lab scale, streamline, and innovate.

To learn more about Janssen’s scientific achievement, and the part that Sapio is playing in it, read the full publication here:

Ultra-High Throughput Bioanalysis in Pharmaceutical R&D – Journal of Chromatography A

Want to see what Sapio LIMS can do for your organization? Request a demo and let us show you how we can support your next scientific breakthrough.