Electronic Lab Notebook (ELN) Software
The market’s most configurable Electronic Lab Notebook simplifies science.
What makes Sapio ELN ® different?
- AI and LLMs
Inside - Advanced Molecular Biology Toolkit
- Unify Data, Powerful Visualizations
- No-Code Workflow
Configuration
ELaiN: AI chat that accelerates science
A truly exceptional ELN should accelerate science by making life in the lab simple. Sapio ELaiN’s built-in AI chat allows scientists to create experiments, manage consumables, integrate data, visualize results, query compound drawings, optimize DNA sequences, query documentation, and even generate code to configure the notebook.
Science-aware tools and objects
More than a single pane of glass, the electronic notebook should deliver built-in scientific applications that provide real utility to scientists without disruption. Sapio ELN ® includes integrated designers for CRISPR, plasmids, compounds, PCR primer, and vector modification, genome browser, and more—empowering scientists to do what they do best.
Scientist-led analysis, not SQL code
Tired of an army of database scientists standing between you and your scientific data? Made for science, not SQL, Sapio ELN ® offers scientists rich data search, visualization, and analysis. Quickly find structured and unstructured data across your entire organization with science-aware™ searching, including the ability to locate compounds by substructure and similarity. Then, bring your data to life in interactive, scientific visualizations—all without ever leaving your ELN.
No-code flexibility
Sapio’s drag-and-drop workflow builder, English sentence rules engine, configurable user interface, and natural language AI-chat, ELaiN, simplify life in the lab. They aid scientists and lab operations in efficiently configuring processes and workflows, improving day-to-day operations, and enhancing data analysis and reporting.
TOP ELN VENDOR
Why do Sapio customers love our configurability and open lab platform?
Features Sapio ELN for simplified data analysis
Reusable experiment templates
ELNs leverage reusable experiment templates to enhance laboratory productivity by enabling scientists to easily create standardized, pre-designed experiment layouts and protocols. Researchers can easily replicate these templates, saving time and ensuring consistency across experiments. This also reduces the risk of human error and ultimately helps make life in the lab easier for busy scientists.
Molecular Biology Toolkit
An enhanced Molecular Biology Toolkit for advanced research – essential for cutting-edge molecular biology projects. It includes CRISPR Design with both annotated and non-annotated multiple sequence alignment views, Plasmid & Compound Design, PCR Primer Design, Golden Gate Assembly, and Vector Modification Tools for precise genetic alterations.
Flow Data Analysis
Flow cytometry data analysis can be a time-intensive task. Using machine learning, Sapio’s Flow ELN assists researchers in efficiently managing and analyzing flow cytometry data by allowing them to input, store, and visualize the results. Researchers can track cell populations, analyze fluorescence intensities, and create graphical representations of the data within the ELN, making it a valuable tool for streamlining the analysis of flow cytometry experiments.
Free Form Note Taking
Observations and ideas don’t always fit neatly into a predefined template. Much like a traditional notebook, ELN software enables users to capture and record information in a flexible and unstructured manner. It permits researchers to make open-format, free-text notes, sketches, or annotations, offering the versatility to document various types of data and insights naturally – without restriction.
AI Scientific Assistant – ELaiN
Sapio ELaiN is an AI-powered assistant built into the Sapio lab informatics platform. With ELaiN, scientists can chat directly with the Sapio ELN—similar to Chat-GPT—to receive instant product support, set up experiments, query any data, analyze data in an instant, or generate custom code in seconds for faster experiment or workflow configuration.
Built-in data visualization
An effective ELN should be equipped with tools to visualize, analyze, and utilize scientific data in a truly scientific way. With Sapio ELN, users can easily interpret complex data with a science-aware knowledge graph that utilizes AI analytics. Save time on repetitive tasks and instead uncover insights that drive forward your research.
The Lab Notebook with Unlimited Flexibility
Sapio no-code ELN is equipped with advanced tools to visualize, analyze, and utilize scientific data in a truly scientific way. Here are some of the features our customers love most.
- Molecular Biology Toolkit:
CRISPR Design- Genome Browser
- Plasmid Design
- PCR Primer Design
- Vector Modification
- Restriction Cloning
- Golden Gate
- NVIDIA BioNeMo NIM microservices
- Document experiments
- Experiment templates
- Realtime collaboration
- Instrument integration
- AI-Chat Assistant ELaiN
- 3D Plating
- Flow cytometry analysis
- Built-in statistical calcs
- SOP and GxP compliance
- Data security
Choose your ELN for specific scientific needs
Whether you work in biotechnology, chemistry, genetic sequencing, in vivo, or bioanalytical studies, discover which ELN solution can encourage collaboration and drive forward scientific analysis across your teams.
Research ELN
Realize the full potential of the digital lab with a scalable ELN that utilizes advanced workflow processes.
Clinical Diagnostic ELN
Our clinical ELN solution enables your diagnostics lab to better manage large volumes of data.
NGS ELN
NGS-ready ELN software that delivers seamless instrument integrations to simplify the complexity of NGS workflows.
Histopathology ELN
Combine no-code workflows and science-aware data management for deeper scientific insights.
In Vivo ELN
Manage in vivo studies with modern ELN software designed for data capture, collaboration, and insights.
Bioanalytical ELN
Our ELN software is designed to support flexible and reproducible bioanalytical studies, no matter the scale or complexity.
Bioprocessing ELN
Our integrated ELN software forms part of a fresh digital solution to improve collaboration and data quality during bioprocessing research.
Stability ELN
ELN software that supports scientists in accelerating and advancing their stability studies, ensuring safe and accessible pharmaceutical products for all.
En otras palabras, Sapio es science-aware™.
Aprenda lo que significa ser un ELN science-aware™ en nuestra guía.
Molecular biology is a fundamental branch of science focusing on biological molecules like DNA, RNA, and proteins and their intricate interactions within cells. For experienced molecular biologists tackling complex research and development challenges in these demanding fields, effective software tools are not just helpful; they are crucial for accelerating scientific progress, enabling faster discovery, more effective design and analysis, and streamlining scientific workflows.
Sapio provides a comprehensive suite of seamless Molecular Biology tools to support these efforts. This toolkit helps users create, edit, and display annotated sequences, facilitate the design of PCR primers, perform various kinds of analysis, and perform molecular cloning procedures. While molecular biology software historically was desktop-based, modern solutions like Sapio’s are based on web browsers and private cloud.
CRISPR Design
The Sapio toolkit includes a CRISPR Wizard designed to assist in CRISPR-related workflows. This tool is often integrated with the Genome Browser. It features capabilities for designing CRISPR gRNAs.
Genome Browser
A general-purpose genome browser is available within the Sapio Molecular Biology Toolkit. This browser is based on the existing CRISPR gRNA designing tool. It provides capabilities for variant visualization. The Genome Browser is accessible via the Sequence Editor.
Sequence Editor
This editor enables users to create, edit, and annotate DNA/RNA and protein sequences, including sequence features. It supports opening sequences from various formats or importing from GenBank, Addgene, and UniProt, visualizing annotated sequences alongside a graphical map. Large sequences of up to 20 million characters are supported. The Sequence Editor offers a range of analysis options and tools.
Vector Modification
The Vector Modification Wizard is a key tool within the Sapio toolkit. It is specifically designed for modifying vectors. The wizard facilitates procedures such as designing PCR primers for site-directed mutagenesis and supports operations like substitution, insertion, deletion, and adding restriction sites.
Restriction Cloning
Sapio’s Restriction Cloning Wizard simplifies the traditional cloning process with a step-by-step visual workflow. Users can easily select source and destination sequences, visualize restriction sites, and preview the resulting construct in real-time after the software automatically suggests suitable combinations of restriction sites for cloning. With support for precise cut-site matching and seamless construct verification, this tool accelerates cloning design while reducing error and complexity.
Multiple Sequence Alignment
Compare and align multiple nucleotide or amino acid sequences with industry-standard algorithms including MAFFT, MUSCLE, Clustal Omega, and BioMSA. Visualize results with rich, interactive graphics featuring annotated pileups, sequence features, and translations. Seamlessly integrated with our Protein Sequence Editor for a streamlined analysis workflow.
Gibson Assembly
This tool supports Single Set Assembly, which automatically designs primers with homology flanks based on the previous and next fragments and simulates the assembly process. It also provides Combinatorial Assembly for sets of parts grouped in bins, verifying feasibility, designing primers, generating all possible combinations, and simulating the assembly. Furthermore, the Split Sequence feature finds suitable split points for optimal primer placement and simulates the assembly.
Golden Gate
Sapio provides a Golden Gate Assembly Wizard. This tool allows users to perform Golden Gate Assembly procedures. It supports designing PCR primers for fragment joining or adding necessary overhangs and cloning sites. Updates to this wizard include support for Entry Plasmid Sets, Combinatorial Assembly, Advanced Assembly, and Split Sequence methods.
PCR Primer Design
Sapio’s toolkit facilitates the design of PCR primers through dedicated tools and wizards. Users can perform manual primer design or utilize the automatic scanning feature. The tool also supports editing existing PCR primers. Automatic PCR primer design running behind the scenes is fundamental for various procedures supported by the toolkit, such as Gibson Assembly, Golden Gate Assembly, and Vector Modification for site-directed mutagenesis.
Codon Optimization
Sapio’s Codon Optimization feature intelligently reverse-translates proteins or modifies existing cDNA sequences to maximize expression yields. It automatically detects and replaces rare codons, optimizes GC content, and removes destabilizing motifs, hairpins, internal polyA signals, and repetitive sequences. This ensures your constructs are biologically efficient and expression-ready in the selected host organism.
Multimodal Registration
Sapio’s advanced molecular biology toolkit is seamlessly integrated with the recently announced multimodal registration to assist scientists in bridging the small molecule—large molecule divide. It enables the efficient management of natural and non-natural biologics, diverse conjugates, peptides, and small molecules.
NVIDIA BioNeMo
The integration of NVIDIA BioNeMo into the Sapio Platform equips scientists with advanced in silico tools embedded directly within their experimental workflows. This includes access to powerful AI-driven models such as DiffDock, an AI-powered molecular docking model, and MolMIM, which enables the design and optimization of small molecules. These tools allow researchers to generate novel candidate molecules early in the research process, predict their 3D protein targets using AlphaFold2, and evaluate docking interactions with target proteins—all within a unified, science-aware platform. By consolidating these capabilities in a single environment, the Sapio Platform streamlines molecular modeling, accelerates the path from discovery to development, and empowers scientists to innovate with greater speed and precision.
The benefits of Sapio ELN are truly immeasurable, but here’s a start.
46%
Rise in System Usability Score (SUS)
251%
Increase in Experiments
10x
Improvement in Productivity
ELN Guides and Advice
Blog Post
The Impact of Configurable Lab Platforms on Biotech Research
Blog Post
LIMS vs ELN: Understanding The Difference & How To Choose The Right One
Blog Post
Electronic Lab Notebook Best Practices: How to Use Your ELN Effectively
Bibliografía y recursos sobre el producto
Brochure
Sapio ELN Product Sheet
Case Study
ImmuneBridge Case Study
Case Study
PTC Therapeutics Case Study
¿Tiene dudas sobre los cuadernos electrónicos de laboratorio?
Con mucho gusto las responderemos.
An electronic lab notebook (ELN) is a digital tool that aids scientists in securely recording and organizing their experimental data, observations, and research notes. ELNs encourage collaboration, as well as enhance data integrity and accessibility, making it a preferred choice over traditional paper notebooks for modern research.
Learn more about ELNs in our comprehensive guide.
Electronic lab notebooks (ELNs) are used by a diverse group of professionals, including scientists in academia, pharmaceutical and biotech companies, chemists, biologists, clinical researchers, environmental scientists, material scientists, engineers, and quality control teams.
Their flexibility and efficiency make them essential for data management, collaboration, and regulatory compliance across a wide range of scientific and research disciplines.
Many view the electronic lab notebook as a pane of glass, a more visual and sophisticated form of the paper notebook. But this definition assumes the ELN is still a passive tool and not an active one. Conversely, a differentiated ELN will not just standardize and digitize traditional lab notes, it will open new possibilities by harmonizing the notebook function with powerful science-aware™ capabilities.
For example, imagine an electronic lab notebook that could support embedded, editable data visualizations, or allow you to design scientific entities that can subsequently be used across all your experiments at scale? Consider a world in which all your scientific observations are highly searchable—with science-aware™ linkages that help you find and use precisely the data you are looking for. Layer on top rich scientific collaboration tools and an integrated platform for LIMS and data management, and you have so much more than a digital version of the lab notebook.
Beyond sheer capability, the ELN is also highly differentiated by its interface. Does it work the way the scientist thinks? If the answer is no, adoption will continue to be an uphill battle. If the answer is yes, then adoption will be unanimous.
Many assert that poor ELN adoption is a byproduct of change-resistant scientists—but this is not the case. Poor ELN adoption is much more the byproduct of poor solutions that either don’t work the way scientists do or fail to provide the enhanced utility needed to justify a change in approach.
Scientists are about anything that accelerates scientific progress. When the ELN becomes a powerful enabler of faster discovery, more effective analysis, and richer scientific collaboration, it will be used by scientists everywhere. In fact, the Sapio ELN is enthusiastically embraced by scientific teams, who recognize its ability to simultaneously simplify and supercharge their daily work.
The biggest thing an ELN needs to provide for scientists to use it is an interface that works the way they do. If a scientist is used to composing experiments in a certain way, for example, the ELN should enable them to do so—only easier and more simply than ever before.
An ELN should also be so much more than a pretty (inter)face. It should provide scientists a variety of Science-aware™ tools that enable them to not only digitize, but enhance, experiments. Take our 3D plater, for example, which enables scientists to assemble plates with automation-enhanced ease. Or our experiment builder, which allows scientists to define and reuse experiments using drag-and-drop. Or our scientific collaboration tools, which allow scientists to rally around their work in a way that a paper notebook never could.
When an ELN provides all these things, scientists will not only use it—they will embrace it wholeheartedly and never look back.
The laboratory notebook is home to a wealth of scientific data, including experimental data points, observations, instrument data, scientific objects, and more. Unfortunately, the traditional lab notebook, and even many electronic lab notebooks, fail to bridge the gap between storing this data and making it usable in more meaningful ways to drive scientific progress throughout the organization.
At Sapio, we recognize that the ELN and the LIMS are inseparable from scientific data management. The data from these solutions must be easy to search, reuse, standardize, analyze, and utilize throughout the organization. Most importantly, these functions should not require scientists to exit the lab informatics platform and outsource scientific data intelligence to another (often non-scientific) solution. Everything should be done in one place—where the data is and where the scientists are.
Learn more about lab data management in our comprehensive guide.
Sapio Sciences’ lab informatics solutions are trusted by some of the world’s largest and fastest growing pharma and biotech companies. Sapio’s technology is backed by deep expertise in the creation of user-friendly applications and an unwavering focus on the priorities and requirements of the scientific user.
Our customers consider Sapio a dedicated partner, and we are committed to transparency and truthfulness in all that we do. Visit our company page to learn more about The Sapio Seven—seven principles that are foundational to our mission and products.
The cost of ELN software varies widely, ranging from free or low-cost options with limited functionality to more expensive solutions, depending on features and scale. It’s crucial to evaluate different options to find one that fits your budget and requirements.
We offer several editions of our platform that can be tailored to each customer’s level of requirements. Check out our pricing page to learn more about pricing and features for our Gold, Silver, and Bronze editions (our Bronze ELN is free for academics).
Our commitment to lowering the barriers to adoption starts during implementation. Our lab informatics platform, including ELN, LIMS, and Scientific Data Cloud, are fully cloud-based and require nothing more than a modern web browser. Simply sign up and get started. Are you an academic? You can register to use our Sapio Bronze edition for free.
Our commitment to lowering the barriers to adoption starts during implementation. Our lab informatics platform, including ELN, LIMS, and Scientific Data Cloud, are fully cloud-based and require nothing more than a modern web browser. Simply sign up and get started. Are you an academic? You can register to use our Sapio Bronze edition for free.
The Sapio ELN is so easy to use and frictionless to adopt, that many scientists find they do not need any training at all.
For customers that are looking for a little extra support, we provide free access to our support forum and helpful resource library. In addition, our resource library provides useful information about ELN and LIMS software and offers customers access to whitepapers and additional support.
Beyond our forum and resource library, the entire Sapio team is dedicated to supporting our customers in meeting their lab informatics-related objectives now and in the future. We consider ourselves true partners and are proud of the level of support
Are you a Sapio Sciences customer and have a question? You can reach our sales and customer support team via email or call us at (410) 800-4620.
The Sapio ELN is so easy to use and frictionless to adopt, that many scientists find they do not need any training at all.
For customers that are looking for a little extra support, we provide free access to our support forum and helpful resource library. In addition, our resource library provides useful information about ELN and LIMS software and offers customers access to whitepapers and additional support.
Beyond our forum and resource library, the entire Sapio team is dedicated to supporting our customers in meeting their lab informatics-related objectives now and in the future. We consider ourselves true partners and are proud of the level of support
Are you a Sapio Sciences customer and have a question? You can reach our sales and customer support team via email or call us at (410) 800-4620.
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