Exemplar Biomarker Discovery
Personalized Medicine - The Future of Drug Development
Discovering key biological markers to predict treatment responders is one of the critical keys to success. Often multi-hundred million or even billion dollar decisions can hinge on the success or failure of being able to properly profile patients to a particular treatment. The lab technology to facilitate such decisions has seen major advances in the last decade in DNA assessment, expression profiling, proteomics and metabolomics.
Unfortunately information technology has lagged in being able to provide a holistic view of all the data starting from the sample through assay. In reality, even the most successful pharmaceutical and biotech companies often have this data in many different data stores ranging from LIMS to custom databases to spreadsheets. This inhibits researchers from doing interrogations across a Study or Studies, Treatment Groups, Subjects, Samples and Assay data and through this holistic view making key biomarker discoveries.
The Solution - Exemplar Biomarker Discovery
In order to realize the goal of personalized medicine researchers need to be empowered with a solution that stores and tracks data about samples and their processing through and including all the diverse assay data that may be generated. Exemplar Biomarker Discovery will handle sample management, but goes beyond that to also track sample processing (i.e. E-Lab Notebook) and managing of other important data including assay data. Exemplar aggregates this important data into a single data store for all Clinical Study, Treatment Group, Subject, Sample and Assay result data. For the assay data, Exemplar has built data loaders for most common platforms being used in modern labs including PCR, Elisa, IHC, Western Blot, Flow Cytometry, etc. Furthermore, Exemplar can exchange data with CRO's for those who outsource some or all of their lab work and supports standardized data formats such as SDTM.
The point of aggregating all this data under one solution is to then be able ask questions of the system that span many different types of data. Exemplar's built-in tools empower researchers to easily query the entire Exemplar system, or any subset of it, for information spanning all Study elements from Study level information through the assay results. This task is made straightforward as researchers do not need to understand database concepts or data structures to be able to build queries. To then make sense of query results, Exemplar integrates key statistics and exploratory analysis to enable true Knowledge Discovery on the aggregated data.
Exemplar Biomarker Discovery is the only solution to provide this comprehensive set of features in one product. This combined with Exemplar's best in class configurable data model and plugin API means that it can be tailored to each clients specific needs quickly and efficiently.
Sapio Sciences - Your Partner in Discovery
Sapio has extensive experience in assisting some of the most successful and well known biotech and pharmaceutical companies in managing their clinical study data and making important discoveries. While we value all settings in which Exemplar is utilized, this area of usage of the Exemplar family of products is particularly inspiring to Sapio's management and employees as a clear and direct connection between the work that is done by Sapio and key discoveries at our customers leading to treatments for cancer and other serious diseases is evident. Sapio will continue to push the boundaries of technology to enable more rapid and informed decisions to be made in the area of biomarker discovery for personalized medicine.
To schedule a demonstration of Exemplar, please contact us at firstname.lastname@example.org.